Searchable abstracts of presentations at key conferences in endocrinology

ea0028oc3.2 | Obesity, thyroid and Addison's disease | SFEBES2012

Post-prandial high fat intake leads to acute exposure to circulating endotoxin in type 2 diabetes mellitus subjects

Harte Alison , Varma Madhusudhan , Tripathi Gyanendra , McGee Kirsty , Al-Daghri Nasser , Al-Attas Omar , Sabico Shaun , O'Hare Joseph , Ceriello Antonio , Saravanan Ponnusamy , Kumar Sudhesh , McTernan Philip

Habitual post-prandial absorption of saturated fatty acids (SFAs) increases systemic atherogenic lipoproteins and a pro-inflammatory response, a condition exacerbated by obesity, insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Also, gut derived bacteria (endotoxin) is absorbed coupled to damaging lipoproteins as it crosses the mucosa, which could directly impact on adipose tissue, as our previous studies suggest. The current studies addressed whether a SFA rich me...